Some individuals may simply have a delayed onset of puberty due to genetic or familial factors. This is often referred to as constitutional delay of growth and puberty (CDGP). Conditions that affect the production or action of hormones involved in puberty, such as thyroid disorders or pituitary gland abnormalities, can lead to delayed puberty. Serious medical conditions such as malnutrition, cystic fibrosis, or chronic kidney disease can delay puberty due to their impact on overall health and hormone levels. Certain genetic conditions, such as Klinefelter syndrome in boys (where there is an extra X chromosome), can delay puberty.
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